Bioweb™

Zeus Bioweb™ is a non-woven composite membrane produced by electrospinning biocompatible PTFE and PU into polymeric nanofibers. Collectively, these nanofibers form a product well-suited for encapsulating implantable stents and scaffolds.

Bioweb™ PTFE/PU composite membranes provide an efficient adhesion platform for stents and scaffolds, enabling low-profile encapsulation over nitinol frames without sutures at a much lower temperature (266 °F / 130 °C) than traditional ePTFE coverings (572 °F / 300 °C). In addition to lower temperature bonding than ePTFE, Bioweb™’s PU layer combined with the PTFE layer provides isotropic mechanical properties, allowing Bioweb™ to encapsulate a wider variety of frames and unique geometries.

As an electrospun product, Bioweb™ possesses excellent isotropic mechanical properties. The electrospinning process produces a composite matrix with microporous qualities similar to that of ePTFE. However, the pores seen in the outer layer of PTFE in Bioweb™ are typically larger (3-5 μm) before sealing, resulting in potentially improved endothelialization when compared to pure ePTFE coverings.

As a global leader in the development and production of advanced medical device components, Zeus provides a wide array of resources, including an extensive network of field application engineers (FAEs), to assist you in bringing your new technologies to the market. Our team will work with you to evaluate your frame structures, confirm our ability to encapsulate them with prototype samples of Bioweb™, and before commercialization, guide you through a fast and easy technology transfer agreement enabling you to cover your own stents or other implantable devices with Bioweb™.

  • APPLICATIONS

    Low-Profile Stent Encapsulation – As a peripheral stent covering, Bioweb™ is well-suited for applications on stents that need the thinnest possible effective encapsulation for new developments.

    Implantable Structures In The Body – The microporous surface of Bioweb™ is ideal for covering a variety of other frames and stents, as well as cardio valves and patches, septal occluders, and more.

  • KEY PROPERTIES

    Biocompatibility – Bioweb™ is made from biocompatible PTFE and PU, is non-toxic, and can safely exist in the body.

    Continuous Membrane or Sheet – This non-woven product is particularly amenable to being formed into sheets or on a continuous roll, allowing for a variety of uses.

    ETO Sterilization – Electrospun PTFE and PU in Bioweb™ can be sterilized with ETO.

    Low Temperature Encapsulation – Bioweb™ stent encapsulations can be performed at lower temperatures (266 °F / 130 °C) compared to traditional ePTFE coverings (572 °F / 300 °C), preventing damage to nitinol stent framework.

    Non-Reactive – Bioweb’s™ minimal chemical reactivity means that this material will not degrade the metal stent (nitinol, cobalt chromium, or stainless steel) framework.

    Porous Structure – Bioweb™’s open pore structure makes this material potentially suited for improved tissue in-growth. Additionally, the porous outer layer made from nanofibers creates an increased interface to potentially allow for better endothelialization when compared to conventional, or stretched, ePTFE products.

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