Absorv™ is our family of bioabsorbable extrusions consisting of tubing, oriented tubing, monofilament, and drawn fiber. Absorv™ products are made from absorbable synthetic polyesters, including poly(L-lactide) (PLLA), poly(glycolide) (PGA), poly-ε-caprolactone (PCL), polydioxanone (PDO), and others. These polymers offer a baseline for the design of copolymers, terpolymers, and blends with mechanical properties and absorption profiles tailored to meet the demands of specific medical applications.
Tubing & Oriented Tubing
Like all of our bioabsorbable products, Absorv™ tubing is capable of safely existing in the body for controlled lengths of time before being absorbed and eliminated naturally. Thanks to this finite functionality, Absorv™ tubing is particularly well-suited for controlled drug release applications where highly targeted and localized treatment is crucial.
Absorv™ XSE oriented tubing takes our standard Absorv™ tubing to the next level. Improved molecular orientation within Absorv™ XSE helps provide enhanced toughness, strength, and uniformity when compared to our previous generation of Absorv™ oriented tubing. With a combination of unmatched sizing, uniform wall thickness, and tailored absorption profiles, Absorv™ XSE oriented tubing is evolving BRS applications and giving designers more efficient and predictable options for replacing metallic stents in a wider variety of procedures spanning cardiovascular, peripheral, ENT, and other fields.
Monofilaments & Drawn Fiber
Bioabsorbable monofilaments have been utilized in the medical device industry for decades, most notably as an alternative to traditional suture materials. These products have also been utilized as an absorbable option for wound closure, or by forming highly oriented monofilament (drawn fiber) into devices such as sinus stents.
When a monofilament with higher tensile strength is needed (up to 5x*), such as in woven mesh devices or formed drug-eluting sinus stents, Absorv™ drawn fiber is available. This high-performance monofilament undergoes an additional step to elongate the fiber after the extrusion process. This extra step of drawing the fiber adds strength and toughness to the fiber, ensuring it is optimized for your specific application needs.
*Based on testing of a nominal size, oriented vs. non-oriented that are not sterilized, not intended to be a specification, actual testing and economic value is subject to change with material(s), sizes, or product types.
With the steady growth and interest in bioabsorbables, applications are always evolving and expanding. At Zeus, we are at the forefront of these developments and will work with you to reach your precise product goals.
Disclaimer: Absorv™ tubing utilizes manufacturing aids made from Class VI PTFE monofilament. As a result, embedded PTFE particulates may be present in the product. Zeus does not warrant that Absorv™ tubing is free of PTFE particulates. Customers must assess the suitability and safety of using Absorv™ tubing products for medical devices.
Bioabsorbable Stents and Occluders – Stents and occluders of customizable shapes and sizes are made possible by the high-strength, tunable stiffness, and unique absorption profiles of bioabsorbable polymers, especially when produced in an oriented/drawn fiber form.
Bioresorbable Vascular Scaffolds – Bioabsorbable polymers are uniquely qualified to be converted into vascular scaffolds that provide temporary luminal support and controlled delivery of anti-proliferative drugs for the treatment of vascular disease, including coronary artery disease (CAD) and peripheral artery disease (PAD).
Controlled Drug Delivery – The wide range of absorption profiles, achieved via polymer design and specialized polymer processing techniques, allows for the creation of highly tailorable degradation-mediated and diffusion-mediated drug delivery vehicles.
Cosmetic Face-lift Fibers – Capable of being produced with various tissue anchoring mechanisms, bioabsorbable drawn fibers are the perfect solution for minimally invasive cosmetic procedures with patient comfort and satisfaction in mind.
Gastrointestinal Devices – Bioabsorbable polymers go big in this arena, paving the way for treatments with large-anatomy devices with tunable structural support and multiple mechanisms of delivery.
Bioabsorbable – A key advantage of bioabsorbable polymers over other materials is their innate ability to be absorbed naturally by the body, eliminating the need for permanent device implantation or for surgical removal at a later date.
Ability to Match Absorption Profile with Healing Profile – In most applications, especially those of a load-bearing nature, the absorption profile and, more specifically, the mechanical integrity-loss profile should coincide with the healing and restoration profile of the tissues being treated.
Tunable Thermal and Mechanical Properties – From homopolymers, to copolymers, to terpolymers, to blends, the precise control over glass transitions and crystallinity allows for polymer morphologies suitable for controlled levels of molecular orientation, leading to optimal mechanical properties such as high strength and toughness.
Controlled Load Transfer – For implants, the interface with bone plays a critical role in how the implant is accepted and functions for long-term well-being. By controlling the degradation rate of implants made with our bioabsorbable materials, the stresses commonly associated with these implants are reduced.
Safely Existing in the Body – Our bioabsorbable products can safely exist in the body for extended periods and elicit no adverse effects, as is often associated with implanted metals. Zeus bioabsorbables are used in FDA-approved medical devices.
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