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Our Absorv® bioabsorbable products are capable of safely existing in the body for controlled lengths of time before being absorbed without causing harm or adverse interactions. These products are particularly suitable for a variety of medical applications and provide an alternative to traditional polymers or metal components.
At Zeus, we partner with our customers to develop novel bioabsorbable polymers to meet precise degradation rates and other specifications.
Most of the commercially available bioabsorbable devices are composed of polyesters, primarily homopolymers and copolymers of poly-L-lactic acid (PLLA) and poly(glycolic acid; PGA). Copolyesters of ε-caprolactone, trimethylene carbonate, and p-dioxanone have also been commercialized. At Zeus, we continue to strive to raise the bar for our bioabsorbable and other product lines.
The Zeus Advantage: Technology and Capabilities
Our bioabsorbable material processing capabilities and formulations are the most advanced in the industry. We are able to extrude these biomaterials into high precision tubular geometries, monofilament, sheets, and microporous non-woven materials. We perform full polymer characterization to provide the necessary data to meet regulatory requirements. Our capabilities include tight tolerance extrusion, formulation, customization, sophisticated materials science, multiple combinations of our products, and controllable degradation profiles.
The Role of Bioabsorbables in Typical Medical Applications
Zeus’ Absorv® bioabsorbable polymers are focused on the development of a wide variety of medical products for both preventive care and disease treatment. These materials are capable of safely existing in and being absorbed by the body for a controllable and finite period of time. Because these materials are bioabsorbable, there is no associated stress shielding as commonly seen with long term and permanent implants.
With the steady growth and interest in bioabsorbables, applications are always evolving and expanding. At Zeus, we are at the forefront of these developments and will work with you to reach your precise product goals.
Dental – Where teeth are concerned, bioabsorbable products fill a vital role for needs including packing, dry socket treatment, and scaffolding.
Long Term or Controlled Rate of Drug Release – Because these devices can be tailored to have an extended lifespan, they are ideal vehicles through which to deliver of drugs and other therapeutic agents in a sustained and controlled manner.
Orthopedic – Our bioabsorbables are especially suitable for broken bones and associated fracture treatments. Fracture fixation plates, pins and screws, bone augmentation, and bioabsorbable nails as scaffolding are all excellent candidate applications for our bioabsorbable products.
Support for Tissue In-Growth – For use directly in the body, our bioabsorbables form the support for initiating and promoting new tissue in-growth to speed healing.
Surgical – For more invasive procedures or serious injury, Zeus bioabsorbable materials provide diverse options not only to affect treatment but to speed recovery; these include treatments ranging from ligament repair, wound closure – including sutures, suture anchors, skin staples, and adhesives – to adhesion barriers, drug delivery, antineoplastic delivery, ligating clips, hemostasis clips, and temporary radio-opaque markers.
Stents – Our bioabsorbable materials can be used for a variety of stents including vascular, coronary, biliary, ureteral, esophageal, and many more.
Tissue Engineering – Because these products are biocompatible, our bioabsorbable line is well-suited for tissue engineering such as for creating 3-D structure; electrospinning, molded, or extruded vascular graft scaffolding; bowel and ureteral anastomosis, directed nerve regeneration, percutaneous devices with limited in-growth, and ex-vivo tissue engineering scaffolds.
- KEY PROPERTIES
Ability to Match Degradation Profile with Healing Profile – Tailoring the degradation rate of your bioabsorbable material product allows physicians to more closely match its duration within the body with the rate of new tissue growth. These matched rates promote tissue differentiation and help to maximize the benefit from your implantable device.
Absence of Stress Shielding (Osteopenia) – Long term and permanent implants can frequently lead to osteopenia, or loss of bone density, due to the reduced stress experienced by the affected bone that has been absorbed by the implant. Because implants incorporating our bioabsorbable products dissipate with time, bone density is less likely to be affected leading to improved recovery.
Controlled Degradation and Bioabsorption – Having the ability to control the degradation rates of our biomaterial products provides flexibility for multiple treatment options ranging from the acute to longer term therapy.
Controlled Load Transfer – For dental implants, the interface with bone plays a critical role in how the implant is accepted and functions for long term well-being. By controlling the degradation rate of implants made with our bioabsorbable materials, the stresses commonly associated with these implants are reduced.
Cost Effective Compared to Metal Equivalents – In lieu of more expensive metal implantable devices, Zeus bioabsorbable materials present a much more practical alternative for these health care applications.
FDA-Approved for Medical Devices – Zeus bioabsorbables are FDA approved as medical devices.
Finite Functionality – Because we can modulate the degradation rates or these products, patients are less likely to experience unwanted interactions and discomfort from these devices.
No Explantation Surgery – As our bioabsorbables are slowly absorbed into the body, there is no need for a second surgery to remove an implanted device made with our biodegradable products.
No Metal Corrosion-Related Interactions with the Body – Because these biocompatible products are not metal, they present no risk of corrosion while the implanted material is being absorbed.
Provides Novel and Alternate IP Position – With this ever-expanding field of biocompatible and absorbable medical devices, our bioabsorbables present an attractive opportunity for invention, novel applications, and intellectual property development.
Safely Existing in the Body – Our bioabsorbable products can safely exist in the body for extended periods and elicit no adverse effects as is often associated with implanted metals.
Tailored to Customer’s Specifications – Our bioabsorbable products can be customized to meet a broad spectrum of specifications including multiple extruded forms, sizes, molded designs, and material strengths.